AdvanCell Strengthens Global Operations with U.S. HQ and Manufacturing Expansion

AdvanCell, a clinical-stage radiopharmaceutical company developing innovative targeted alpha therapies for cancer, announced the establishment of its U.S. Global Headquarters in the Greater Boston area, and the lease of a new 128,000-square-foot facility that will become the Company’s U.S. flagship manufacturing center supporting its long-term growth and commercialization strategy. The expansion marks an important milestone in the Company’s evolution into a U.S.-based radiopharmaceutical company with integrated operations spanning North America and Australia.

The Andover facility will serve as the Company’s U.S. Global Headquarters, bringing together corporate operations and state-of-the-art manufacturing capabilities.

“Establishing AdvanCell’s U.S. Global Headquarters and future manufacturing facility reinforces our commitment to U.S. expansion and represents an important milestone in AdvanCell’s strategy to build a global, vertically integrated targeted alpha therapy company,” said Philina Lee, PhD, CEO of AdvanCell. “As we advance ADVC001 and our broader Lead-212 pipeline, our Andover facility will be a cornerstone of our U.S. expansion and our first internal manufacturing site in the U.S., providing the foundation to scale production to support future clinical and commercial demand. We will continue to leverage the strengths of our Australian operations – including rapid clinical translation, isotope supply capabilities and process innovation – as we advance our Lead-212 targeted alpha therapies for patients globally.”

As part of its U.S. manufacturing expansion strategy, AdvanCell is also working with a leading contract development and manufacturing organization (CDMO) to establish drug product manufacturing capabilities in addition to the Andover facility fit out and qualification. This approach is expected to accelerate access to U.S.-based manufacturing capacity, supporting Phase 2 enrolment of the TheraPb study (NCT05720130) in the U.S. while the Company further builds its Phase 3 and commercial manufacturing infrastructure.